Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115977 | 0.90 | S1PR1 (0.58) | S1PR1S1PR5S1PR3 | |
| SCHEMBL2605669 | 0.90 | S1PR1 (0.47) | S1PR1S1PR5S1PR3 | |
| SCHEMBL2605718 | 0.89 | S1PR1 (0.44) | S1PR1S1PR5S1PR3 | |
| SCHEMBL2605666 | 0.87 | S1PR1 (0.46) | S1PR1S1PR5S1PR3 | |
| SCHEMBL2115107 | 0.85 | S1PR1 (0.61) | S1PR1S1PR5S1PR3 | |
| SCHEMBL2121453 | 0.83 | S1PR1 (0.60) | S1PR1S1PR5S1PR3 | |
| SCHEMBL2605656 | 0.82 | S1PR1 (0.57) | S1PR1S1PR5S1PR3 | |
| SCHEMBL2118883 | 0.82 | S1PR1 (0.68) | S1PR1S1PR5S1PR3 | |
| SCHEMBL10100445 | 0.81 | S1PR1 (0.71) | S1PR1S1PR5 | |
| SCHEMBL2123115 | 0.81 | S1PR1 (0.68) | S1PR1S1PR5S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010145202-A1 | THIAZOLE OR THIADIZALOE DERIVATIVES FOR USE AS SPHINGOSINE 1-PHOSPHATE 1 (S1P1) RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2010-12-23 | — | — | WO | disclosed |