Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13645791 | 0.82 | ADORA2A (0.57) | ADORA2AADORA3ADORA1 | |
| SCHEMBL13713051 | 0.80 | ADORA2A (0.51) | ADORA2AADORA3ADORA1 | |
| SCHEMBL14947643 | 0.80 | ADORA2A (0.59) | ADORA2AADORA3ADORA1 | |
| SCHEMBL12374999 | 0.80 | ADORA2A (0.59) | ADORA2AADORA3ADORA1 | |
| SCHEMBL13657170 | 0.76 | ADORA2A (0.51) | ADORA2AADORA3ADORA1 | |
| SCHEMBL12375002 | 0.76 | ADORA2A (0.51) | ADORA2AADORA3ADORA1 | |
| SCHEMBL13657202 | 0.76 | ADORA2A (0.51) | ADORA2AADORA3ADORA1 | |
| SCHEMBL12374908 | 0.76 | ADORA2A (0.51) | ADORA2AADORA3ADORA1 | |
| SCHEMBL12373543 | 0.75 | ADORA2A (0.50) | ADORA2AADORA3ADORA1 | |
| SCHEMBL13657205 | 0.75 | ADORA2A (0.50) | ADORA2AADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266994-A1 | 2-propynyl adenosine analgos with modified 5'-ribose groups having A2A agonist activity | University Of Virginia Patent Foundation (US) | 2010-12-29 | — | — | EP | disclosed |