Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 10/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 9/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12979070 | 0.84 | SMPD3 (0.42) | SMPD3IRAK4FLT3 | |
| SCHEMBL851080 | 0.84 | SMPD3 (0.42) | SMPD3IRAK4FLT3 | |
| SCHEMBL851079 | 0.84 | SMPD3 (0.42) | SMPD3IRAK4FLT3 | |
| SCHEMBL13021379 | 0.84 | IRAK4 (0.39) | SMPD3IRAK4FLT3 | |
| SCHEMBL860962 | 0.79 | SMPD3 (0.41) | SMPD3IRAK4FLT3 | |
| SCHEMBL12979127 | 0.79 | SMPD3 (0.41) | SMPD3IRAK4FLT3 | |
| SCHEMBL860963 | 0.79 | SMPD3 (0.41) | SMPD3IRAK4FLT3 | |
| SCHEMBL860108 | 0.79 | SMPD3 (0.50) | SMPD3IRAK4FLT3 | |
| SCHEMBL14679091 | 0.75 | SMPD3 (0.39) | SMPD3IRAK4FLT3 | |
| SCHEMBL861193 | 0.73 | SMPD3 (0.51) | SMPD3IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367681-B2 | Pyrazolopyrimidines and related heterocycles as kinase inhibitors | CYLENE PHARMACEUTICALS, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-20100331314-A1 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | SENHWA BIOSCIENCES, INC. (TW) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331314-A1 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | PIM1, PIM2, PIM3 | SMPD3 4539/4885IRAK4 112/4885FLT3 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.