SCHEMBL13024728

SCHEMBL13024728

CCC(C)C(=O)OCCc1ccc(OC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
EPHX2 P34913 2/20 0.36
EPHX1 P07099 1/20 0.36
STS P08842 1/20 0.35
PPARA Q07869 6/20 0.34
PPARG P37231 5/20 0.34
PPARD Q03181 2/20 0.34
HRH3 Q9Y5N1 2/20 0.34
NPC1 O15118 1/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ALOX5 P09917 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13024731 1.00 CA1 (0.42) CA1CA2EPHX2EPHX1STS
SCHEMBL13125197 1.00 CA1 (0.42) CA1CA2EPHX2EPHX1STS
SCHEMBL13024727 0.97 CA1 (0.40) CA1CA2EPHX2EPHX1STS
SCHEMBL13024729 0.93 CA1 (0.36) CA1CA2EPHX2EPHX1PPARA
SCHEMBL13024722 0.88 CA1 (0.40) CA1CA2EPHX2EPHX1STS
SCHEMBL13823127 0.88 CA1 (0.39) CA1CA2EPHX1STSPPARA
SCHEMBL13376839 0.86 CA1 (0.38) CA1CA2EPHX2EPHX1STS
SCHEMBL13024740 0.84 ELANE (0.36) EPHX2EPHX1PPARAPPARGHRH3
SCHEMBL13024726 0.83 CA1 (0.40) CA1CA2EPHX2STSPPARA
SCHEMBL13024724 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7838190-B2 Electrophotographic photosensitive member with surface layer of fluororesin particles and polyolefin with perfluoroalkyl group CANON KABUSHIKI KAISHA (JP) 2010-11-23 US disclosed
US-7799496-B2 Electrophotographic photosensitive member, method of manufacturing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2010-09-21 US disclosed
US-7704657-B2 Electrophotographic photosensitive member, method of manufacturing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2010-04-27 US disclosed
US-20090180800-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-07-16 US disclosed
US-7553594-B2 Electrophotographic photosensitive member, method of manufacturing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2009-06-30 US disclosed
US-20090130576-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-05-21 US disclosed
US-20080199794-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2008-08-21 US disclosed
US-20080199795-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2008-08-21 US disclosed