Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30294088 | 1.00 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL30294076 | 1.00 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL27386200 | 1.00 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL10339369 | 1.00 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9302438 | 1.00 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL24465248 | 1.00 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL13024899 | 1.00 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9301638 | 0.98 | TSHR (0.67) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL8373745 | 0.92 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL17538840 | 0.87 | TSHR (0.68) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838190-B2 | Electrophotographic photosensitive member with surface layer of fluororesin particles and polyolefin with perfluoroalkyl group | CANON KABUSHIKI KAISHA (JP) | 2010-11-23 | — | — | US | disclosed |
| US-20090130576-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2009-05-21 | — | — | US | disclosed |