Dimethylamine

Dimethylamine

SCHEMBL1302845

C=CC(=O)OC(C)Cl.CNC

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.42
HPGD P15428 1/20 0.32
ALDH1A1 P00352 4/20 0.31
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
CYP3A4 P08684 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10769092 0.93
SCHEMBL393935 0.93
SCHEMBL15841394 0.91
Methylamine SCHEMBL21925184 0.89 TSHR (0.43) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL15641106 0.87 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
Trimethylammonium SCHEMBL936664 0.87 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
Dimethylamine SCHEMBL10504342 0.82 HCAR2 (0.46) TSHRHPGDALDH1A1TP53HIF1A
Dimethylamine SCHEMBL1301203 0.81 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8941388 0.80 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
Dimethylamine SCHEMBL1303029 0.78 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2387866-A1 ELECTROMAGNETIC WAVE SHIELDING GEL-LIKE COMPOSITION 3M Innovative Properties Company (US) 2011-11-23 EP disclosed
US-20110268950-A1 Electromagnetic Wave Shielding Gel-Like Composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-11-03 US disclosed
US-8038066-B2 Laser scanner with deformable lens HAND HELD PRODUCTS, INC. (US) 2011-10-18 US disclosed
WO-2010083075-A1 ELECTROMAGNETIC WAVE SHIELDING GEL-LIKE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-07-22 WO disclosed