⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12320147 | 1.00 | — | — | |
| SCHEMBL733514 | 1.00 | — | — | |
| SCHEMBL13431581 | 1.00 | — | — | |
| SCHEMBL12522128 | 1.00 | — | — | |
| SCHEMBL17931761 | 0.85 | — | — | |
| SCHEMBL20158799 | 0.75 | — | — | |
| SCHEMBL20158766 | 0.75 | — | — | |
| SCHEMBL14210696 | 0.75 | — | — | |
| SCHEMBL14944931 | 0.73 | — | — | |
| SCHEMBL14944945 | 0.73 | CYP3A4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853418-B2 | Cyclopentylpyrazoles as N-type calcium channel blockers | JANSSEN PHARMACEUTICA NV (BE) | 2014-10-07 | — | — | US | disclosed |
| EP-2239565-B1 | OPTICAL-ISOMER SEPARATING AGENT FOR CHROMATOGRAPHY AND PROCESS FOR PRODUCING THE SAME | UNIV OKAYAMA NAT UNIV CORP (JP) | 2014-08-27 | — | — | EP | disclosed |
| US-20140051660-A1 | CYCLOPENTYLPYRAZOLES AS N-TYPE CALCIUM CHANNEL BLOCKERS | JANSSEN PHARMACEUTICA NV (BE) | 2014-02-20 | — | — | US | disclosed |
| US-8362237-B2 | Optical-isomer separating agent for chromatography and process for producing the same | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2013-01-29 | — | — | US | disclosed |
| US-8362237-B2 | Optical-isomer separating agent for chromatography and process for producing the same | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2013-01-29 | — | — | US | disclosed |
| US-20100292464-A1 | OPTICAL-ISOMER SEPARATING AGENT FOR CHROMATOGRAPHY AND PROCESS FOR PRODUCING THE SAME | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2010-11-18 | — | — | US | disclosed |
| US-20100292464-A1 | OPTICAL-ISOMER SEPARATING AGENT FOR CHROMATOGRAPHY AND PROCESS FOR PRODUCING THE SAME | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2010-11-18 | — | — | US | disclosed |
| EP-2239565-A1 | OPTICAL-ISOMER SEPARATING AGENT FOR CHROMATOGRAPHY AND PROCESS FOR PRODUCING THE SAME | National University Corporation Okayama University (JP) | 2010-10-13 | — | — | EP | disclosed |