⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromomethane SCHEMBL6416803 | 0.83 | — | — | |
| Bromomethane SCHEMBL3738968 | 0.71 | — | — | |
| Bromomethane SCHEMBL2981823 | 0.71 | — | — | |
| Bromomethane SCHEMBL17770700 | 0.71 | — | — | |
| Bromomethane SCHEMBL1744 | 0.71 | — | — | |
| Bromomethane SCHEMBL11584708 | 0.61 | — | — | |
| Bromomethane SCHEMBL42155 | 0.61 | — | — | |
| Bromomethane SCHEMBL9703636 | 0.61 | — | — | |
| Bromomethane SCHEMBL8720231 | 0.61 | — | — | |
| Bromomethane SCHEMBL10615072 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324229-B2 | Alkylthio pyrimidines as CRTH2 antagonists | ACTIMIS PHARMACEUTICALS, INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-8076330-B2 | Dipeptidyl peptidase-IV inhibitors | AMGEN INC. (US) | 2011-12-13 | — | — | US | disclosed |
| US-20110112051-A1 | Dipeptidyl Peptidase-IV Inhibitors | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2011-05-12 | — | — | US | disclosed |
| US-20100298361-A1 | Alkylthio Pyrimidines As CRTH2 Antagonists | GB005, INC. | 2010-11-25 | — | — | US | disclosed |
| US-7834031-B2 | Radiolabeled glycine transporter inhibitors | MERCK SHARP & DOHME CORP. (US) | 2010-11-16 | — | — | US | disclosed |
| US-20100009961-A1 | DIPEPTIDYL PEPTIDASE-IV INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2010-01-14 | — | — | US | disclosed |
| US-20090269278-A1 | Radiolabeled Glycine Trasporter Inhibitors | MERCK SHARP & DOHME LLC | 2009-10-29 | — | — | US | disclosed |
| US-7553861-B2 | Dipeptidyl peptidase-IV inhibitors | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2009-06-30 | — | — | US | disclosed |
| US-20090062325-A1 | DEUTERIUM-ENRICHED TIOTROPIUM | PROTIA, LLC (US) | 2009-03-05 | — | — | US | disclosed |
| US-7365091-B2 | Derivatives of succinic and glutaric acids and analogs thereof useful as inhibitors of PHEX | ENOBIA PHARMA (CA) | 2008-04-29 | — | — | US | disclosed |
| US-20070060618-A1 | Alkyne derivatives as tracers for metabotropic glutamate receptor binding | MERCK & CO., INC. (US) | 2007-03-15 | — | — | US | disclosed |