Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 9/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL100281 | 0.92 | CHRM3 (0.54) | CHRM3CHRM1CHRM2CHRM4TSHR | |
| SCHEMBL101568 | 0.91 | CHRM3 (0.51) | CHRM3CHRM1CHRM2ADRB2CHRM4 | |
| SCHEMBL130581 | 0.91 | CHRM3 (0.51) | CHRM3CHRM1CHRM2ADRB2CHRM4 | |
| SCHEMBL98251 | 0.91 | CHRM3 (0.56) | CHRM3CHRM1CHRM2CHRM4TSHR | |
| SCHEMBL98250 | 0.91 | CHRM3 (0.56) | CHRM3CHRM1CHRM2CHRM4TSHR | |
| SCHEMBL98861 | 0.91 | CHRM3 (0.50) | CHRM3CHRM1CHRM2ADRB2CHRM4 | |
| SCHEMBL102482 | 0.90 | CHRM3 (0.60) | CHRM3CHRM1CHRM2ADRB2CHRM4 | |
| SCHEMBL102481 | 0.90 | CHRM3 (0.60) | CHRM3CHRM1CHRM2ADRB2CHRM4 | |
| SCHEMBL130483 | 0.90 | CHRM3 (0.52) | CHRM3CHRM1CHRM2CHRM4TSHR | |
| SCHEMBL98655 | 0.90 | CHRM3 (0.52) | CHRM3CHRM1CHRM2CHRM4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | disclosed |