Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.67 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.67 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13036486 | 0.88 | SLC22A12 (0.77) | SLC22A12SLC22A6SLC22A8KCNH2POLB | |
| SCHEMBL1190488 | 0.87 | SLC22A12 (0.79) | SLC22A12SLC22A6SLC22A8KCNH2POLB | |
| SCHEMBL1191676 | 0.86 | SLC22A12 (0.67) | SLC22A12SLC22A6SLC22A8KCNH2POLB | |
| SCHEMBL1190085 | 0.86 | SLC22A12 (0.67) | SLC22A12SLC22A6SLC22A8KCNH2POLB | |
| Bromide SCHEMBL1190077 | 0.86 | SLC22A12 (0.77) | SLC22A12SLC22A6SLC22A8KCNH2POLB | |
| Bromide SCHEMBL1190540 | 0.85 | SLC22A12 (0.65) | SLC22A12SLC22A6SLC22A8KCNH2POLB | |
| SCHEMBL13037469 | 0.85 | SLC22A12 (0.87) | SLC22A12SLC22A6SLC22A8KCNH2POLB | |
| SCHEMBL1191088 | 0.84 | SLC22A12 (0.63) | SLC22A12SLC22A6SLC22A8KCNH2POLB | |
| SCHEMBL1190582 | 0.83 | SLC22A12 (0.71) | SLC22A12SLC22A6SLC22A8KCNH2POLB | |
| SCHEMBL1191479 | 0.82 | SLC22A12 (0.61) | SLC22A12SLC22A6SLC22A8KCNH2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266989-A2 | HETEROCYCLIC DERIVATIVES | C&c Research Laboratories (KR) | 2010-12-29 | — | — | EP | disclosed |