Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278884 | 0.89 | CHRM3 (0.77) | CHRM3 | |
| SCHEMBL13590160 | 0.87 | CHRM3 (0.69) | CHRM3 | |
| SCHEMBL13590495 | 0.87 | CHRM3 (0.76) | CHRM3 | |
| SCHEMBL13590543 | 0.86 | CHRM3 (1.00) | CHRM3 | |
| SCHEMBL13590238 | 0.86 | CHRM3 (0.87) | CHRM3 | |
| SCHEMBL13590463 | 0.85 | CHRM3 (0.77) | CHRM3 | |
| SCHEMBL266147 | 0.85 | CHRM3 (0.80) | CHRM3 | |
| SCHEMBL14265637 | 0.84 | CHRM3 (0.76) | CHRM3 | |
| SCHEMBL739634 | 0.84 | CHRM3 (1.00) | CHRM3 | |
| SCHEMBL13590162 | 0.84 | CHRM3 (0.89) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829583-B2 | Biphenyl-2-ylcarbamic acid 1-{7-[(R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]heptyl}piperidin-4-yl ester; beta 2 adrenergic receptor agonist and muscarinic receptor antagonist; bronchodilator agent; pulmonary disorders, chronic obstructive pulmonary disease and asthma | THERAVANCE, INC. (US) | 2010-11-09 | — | — | US | disclosed |
| US-7829583-B2 | Biphenyl-2-ylcarbamic acid 1-{7-[(R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]heptyl}piperidin-4-yl ester; beta 2 adrenergic receptor agonist and muscarinic receptor antagonist; bronchodilator agent; pulmonary disorders, chronic obstructive pulmonary disease and asthma | THERAVANCE, INC. (US) | 2010-11-09 | — | — | US | disclosed |
| US-7507751-B2 | Biphenyl-2-ylcarbamic acid 1-{7-[(R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]heptyl}piperidin-4-yl ester; beta 2 adrenergic receptor agonist and muscarinic receptor antagonist; bronchodilator agent; pulmonary disorders, chronic obstructive pulmonary disease and asthma | THERAVANCE, INC. (US) | 2009-03-24 | — | — | US | disclosed |
| US-7507751-B2 | Biphenyl-2-ylcarbamic acid 1-{7-[(R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]heptyl}piperidin-4-yl ester; beta 2 adrenergic receptor agonist and muscarinic receptor antagonist; bronchodilator agent; pulmonary disorders, chronic obstructive pulmonary disease and asthma | THERAVANCE, INC. (US) | 2009-03-24 | — | — | US | disclosed |
| US-7355046-B2 | Chronic obstructive pulmonary dusease; asthma | THERAVANCE, INC. (US) | 2008-04-08 | — | — | US | disclosed |
| US-7355046-B2 | Chronic obstructive pulmonary dusease; asthma | THERAVANCE, INC. (US) | 2008-04-08 | — | — | US | disclosed |
| US-7345175-B2 | Biphenyl derivatives | THERAVANCE, INC. (US) | 2008-03-18 | — | — | US | disclosed |