Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 16/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 12/20 | 0.48 |
| ▸ | KDR | P35968 | 12/20 | 0.48 |
| ▸ | FLT1 | P17948 | 7/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | STK25 | O00506 | 1/20 | 0.39 |
| ▸ | CIT | O14578 | 1/20 | 0.39 |
| ▸ | RIOK3 | O14730 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | GAK | O14976 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | MUSK | O15146 | 1/20 | 0.39 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13042507 | 0.97 | FGFR1 (0.46) | FGFR1PDGFRBKDRFLT1PDE3B | |
| SCHEMBL13042412 | 0.90 | FGFR1 (0.43) | FGFR1PDGFRBKDRFLT1JAK1 | |
| SCHEMBL13042436 | 0.89 | FGFR1 (0.46) | FGFR1PDGFRBKDRFLT1PDE3B | |
| SCHEMBL13042443 | 0.89 | FGFR1 (0.47) | FGFR1PDGFRBKDRFLT1LCK | |
| SCHEMBL13042543 | 0.89 | FGFR1 (0.56) | FGFR1PDGFRBKDRFLT1PDE3B | |
| SCHEMBL13042381 | 0.89 | FGFR1 (0.61) | FGFR1PDGFRBKDRFLT1LCK | |
| SCHEMBL13042438 | 0.88 | FGFR1 (0.49) | FGFR1PDGFRBKDRFLT1LCK | |
| SCHEMBL13042420 | 0.88 | FGFR1 (0.48) | FGFR1PDGFRBKDRFLT1LCK | |
| SCHEMBL13042328 | 0.88 | FGFR1 (0.47) | FGFR1PDGFRBKDRFLT1LCK | |
| SCHEMBL13042439 | 0.87 | CHEK2 (0.47) | FGFR1PDGFRBKDRFLT1CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492374-B2 | Azaazulene compounds | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2013-07-23 | — | — | US | disclosed |
| US-8492374-B2 | Azaazulene compounds | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2013-07-23 | — | — | US | disclosed |
| US-20100280012-A1 | AZAAZULENE COMPOUNDS | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2010-11-04 | — | — | US | disclosed |
| US-20100280012-A1 | AZAAZULENE COMPOUNDS | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280012-A1 | AZAAZULENE COMPOUNDS | AZI2, CYP51A1, CYP3A5 | FGFR1 1577/4885PDGFRB 2688/4885KDR 3950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.