⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13043331 | 0.86 | BRD4 (0.48) | — | |
| SCHEMBL13043333 | 0.85 | BRD4 (0.41) | — | |
| SCHEMBL818956 | 0.75 | — | — | |
| SCHEMBL9336470 | 0.74 | — | — | |
| SCHEMBL28332039 | 0.73 | — | — | |
| SCHEMBL5994539 | 0.71 | KMT2A (0.33) | — | |
| SCHEMBL8668621 | 0.68 | — | — | |
| SCHEMBL24131854 | 0.68 | BRD4 (0.33) | — | |
| SCHEMBL24131989 | 0.67 | BRD4 (0.32) | — | |
| SCHEMBL2919522 | 0.67 | BRD4 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3559082-A1 | CONTINUOUS FLOW PROCESS FOR THE POLYMERIZATION OF AN ALKYLENE OXIDE | Université de Liège (BE) | 2019-10-30 | — | — | EP | claimed |
| WO-2018114416-A1 | CONTINUOUS FLOW PROCESS FOR THE POLYMERIZATION OF AN ALKYLENE OXIDE | Université de Liège (BE) | 2018-06-28 | — | — | WO | claimed |
| WO-2021257696-A1 | ISOFORM-SPECIFIC ALDEHYDE DEHYDROGENASE INHIBITORS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-12-23 | — | — | WO | disclosed |
| US-8450070-B2 | Method for screening of cell-protecting agent | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-05-28 | — | — | US | disclosed |
| US-8450070-B2 | Method for screening of cell-protecting agent | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-05-28 | — | — | US | disclosed |
| CN-102227506-A | Screening assays for identification of bace2 inhibitors | HOFFMANN LA ROCHE | 2011-10-26 | — | — | CN | disclosed |
| US-20100279311-A1 | METHOD FOR SCREENING OF CELL-PROTECTING AGENT | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-11-04 | — | — | US | disclosed |
| US-20100279311-A1 | METHOD FOR SCREENING OF CELL-PROTECTING AGENT | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-11-04 | — | — | US | disclosed |
| WO-2009084653-A1 | METHOD FOR SCREENING OF CELL-PROTECTING AGENT | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-07-09 | — | — | WO | disclosed |