SCHEMBL13045286

SCHEMBL13045286

c1ccc(-c2cc(-c3ccc4ccc(-c5ccccc5)nc4n3)cc(-c3ccc4ccc(-c5ccccc5)nc4n3)c2)cc1

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
RAB9A P51151 2/20 0.48
ADORA2A P29274 2/20 0.42
ADORA1 P30542 2/20 0.42
ALDH1A1 P00352 2/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALK Q9UM73 1/20 0.41
ASIC3 Q9UHC3 1/20 0.41
KDM4E B2RXH2 1/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
PKM P14618 1/20 0.40
CYP19A1 P11511 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13045255 0.98 MEN1 (0.44) MEN1KMT2ARAB9AADORA2AADORA1
SCHEMBL13045223 0.98 MEN1 (0.44) MEN1KMT2ARAB9AADORA2AADORA1
SCHEMBL13045291 0.96 MEN1 (0.48) MEN1KMT2ARAB9AADORA2AADORA1
SCHEMBL13045287 0.96 MEN1 (0.52) MEN1KMT2ARAB9AADORA2AADORA1
SCHEMBL13045288 0.89 MEN1 (0.54) MEN1KMT2ARAB9AADORA2AADORA1
SCHEMBL12915446 0.89 MEN1 (0.59) MEN1KMT2ARAB9AADORA2AADORA1
SCHEMBL13045285 0.87 MEN1 (0.56) MEN1KMT2ARAB9AADORA2AADORA1
SCHEMBL19820841 0.83 MEN1 (0.52) MEN1KMT2ARAB9AADORA2AADORA1
SCHEMBL13045253 0.82 CYP11B1 (0.46) MEN1KMT2AALDH1A1HPGDL3MBTL1
SCHEMBL20250397 0.79 PARP1 (0.49) MEN1KMT2ARAB9AADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7833634-B2 1,8-naphthyridine compound and organic light-emitting device using the same CANON KABUSHIKI KAISHA (JP) 2010-11-16 US disclosed
US-7833634-B2 1,8-naphthyridine compound and organic light-emitting device using the same CANON KABUSHIKI KAISHA (JP) 2010-11-16 US disclosed