Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3685547 | 0.93 | MAP2K1 (0.79) | MAP2K1 | |
| SCHEMBL3686689 | 0.92 | MAP2K1 (0.78) | MAP2K1 | |
| SCHEMBL3688272 | 0.91 | MAP2K1 (0.69) | MAP2K1 | |
| SCHEMBL3686507 | 0.90 | MAP2K1 (0.69) | MAP2K1 | |
| SCHEMBL3682244 | 0.88 | MAP2K1 (0.67) | MAP2K1 | |
| SCHEMBL3694304 | 0.88 | MAP2K1 (0.75) | MAP2K1 | |
| SCHEMBL3685085 | 0.86 | MAP2K1 (0.79) | MAP2K1 | |
| SCHEMBL3685556 | 0.85 | MAP2K1 (0.78) | MAP2K1 | |
| SCHEMBL3694975 | 0.84 | MAP2K1 (0.75) | MAP2K1 | |
| SCHEMBL3684912 | 0.84 | MAP2K1 (0.75) | MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578351-B1 | PYRROLOPYRIDAZINE COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | BRISTOL MYERS SQUIBB CO (US) | 2010-12-08 | — | — | EP | disclosed |