Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13045211 | 0.89 | MAP2K1 (1.00) | MAP2K1 | |
| SCHEMBL3692710 | 0.89 | MAP2K1 (1.00) | MAP2K1 | |
| SCHEMBL3691117 | 0.89 | MAP2K1 (0.80) | MAP2K1 | |
| SCHEMBL5138612 | 0.87 | MAP2K1 (0.82) | MAP2K1 | |
| SCHEMBL3688790 | 0.84 | MAP2K1 (0.87) | MAP2K1 | |
| SCHEMBL3690055 | 0.84 | MAP2K1 (0.83) | MAP2K1 | |
| SCHEMBL3693408 | 0.84 | MAP2K1 (1.00) | MAP2K1 | |
| SCHEMBL3693846 | 0.83 | MAP2K1 (0.82) | MAP2K1 | |
| SCHEMBL3693390 | 0.83 | MAP2K1 (0.85) | MAP2K1 | |
| SCHEMBL6054361 | 0.83 | MAP2K1 (0.85) | MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578351-B1 | PYRROLOPYRIDAZINE COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | BRISTOL MYERS SQUIBB CO (US) | 2010-12-08 | — | — | EP | disclosed |