Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 14/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 12/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.55 |
| ▸ | PI4KA | P42356 | 4/20 | 0.55 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.55 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.55 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402912 | 0.79 | ADORA2A (0.66) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL4239755 | 0.77 | ADORA2A (0.68) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL29439771 | 0.74 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL18520815 | 0.74 | ADORA2A (0.64) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL8832637 | 0.74 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL2980005 | 0.74 | ADORA2A (0.64) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL25665342 | 0.74 | ADORA2A (0.64) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL19533412 | 0.73 | LRRK2 (0.48) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL18165665 | 0.71 | ADORA2A (0.60) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL4064829 | 0.71 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADORA3PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851152-B2 | Fluorescent base analogues' usage in the characterization of nucleic acid molecules and their interactions | CHEN YAODONG | 2010-12-14 | — | — | US | disclosed |