Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 3/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.45 |
| ▸ | SYK | P43405 | 4/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 8/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13048816 | 0.92 | BRD4 (0.39) | PIK3CGSYKMERTKCSNK2A1USP2 | |
| SCHEMBL13048821 | 0.91 | MERTK (0.48) | SYKMERTKCSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL13048799 | 0.86 | SYK (0.44) | PIK3CGGSK3BSYKMERTKUSP2 | |
| SCHEMBL13048811 | 0.85 | SYK (0.44) | PIK3CGSYKMERTKUSP2CYP1A2 | |
| SCHEMBL13048648 | 0.84 | PIK3CD (0.43) | PIK3CGMAPK8SYKCSNK2A1PIK3CD | |
| SCHEMBL13048813 | 0.82 | SYK (0.44) | SYK | |
| SCHEMBL13048641 | 0.82 | SYK (0.45) | PIK3CGSYKMERTKCSNK2A1MAPK1 | |
| SCHEMBL13048627 | 0.82 | PIK3CD (0.41) | PIK3CGMAPK8SYKCSNK2A1PIK3CD | |
| SCHEMBL13048207 | 0.80 | SYK (0.54) | SYK | |
| SCHEMBL13048808 | 0.80 | SYK (0.55) | PIK3CGSYKMERTKCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298557-A1 | PYRAZOLOPYRIMIDINE COMPOUND | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2010-11-25 | — | — | US | disclosed |
| US-20100298557-A1 | PYRAZOLOPYRIMIDINE COMPOUND | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298557-A1 | PYRAZOLOPYRIMIDINE COMPOUND | SYK, LCK, FYN | PIK3CG 517/4885MAPK8 241/4885GSK3B 753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.