Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 7/20 | 0.33 |
| ▸ | MMP13 | P45452 | 7/20 | 0.33 |
| ▸ | MMP1 | P03956 | 6/20 | 0.33 |
| ▸ | MMP3 | P08254 | 6/20 | 0.33 |
| ▸ | MMP9 | P14780 | 6/20 | 0.33 |
| ▸ | MMP7 | P09237 | 5/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18412644 | 1.00 | CA14 (0.43) | CA14CA12CA7CA9ADAM17 | |
| SCHEMBL5839741 | 0.81 | KDM4E (0.49) | CA14CA12KDM4EMMP2MMP13 | |
| SCHEMBL5839738 | 0.81 | KDM4E (0.49) | CA14CA12KDM4EMMP2MMP13 | |
| SCHEMBL13049836 | 0.81 | CA14 (0.43) | CA14CA12CA7CA9ADAM17 | |
| SCHEMBL158435 | 0.79 | CA14 (0.42) | CA14CA12CA7CA9ADAM17 | |
| SCHEMBL1864824 | 0.79 | CA14 (0.42) | CA14CA12CA7CA9ADAM17 | |
| SCHEMBL1074659 | 0.79 | CA14 (0.42) | CA14CA12CA7CA9ADAM17 | |
| SCHEMBL6312414 | 0.79 | CA14 (0.42) | CA14CA12CA7CA9ADAM17 | |
| SCHEMBL17066709 | 0.77 | CA14 (0.41) | CA14CA12CA7CA9CA2 | |
| SCHEMBL15491572 | 0.77 | CA14 (0.73) | CA14CA12CA7CA9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138791-A1 | ANTIVIRAL COMPOUNDS COMPOSED OF THREE LINKED ARYL MOIETIES TO TREAT DISEASES SUCH AS HEPATITIS C | SCHERING CORPORATION (US) | 2010-12-02 | — | — | WO | disclosed |