Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TNKS | O95271 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | SULT2A1 | Q06520 | 1/20 | 0.51 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.51 |
| ▸ | AXIN2 | Q9Y2T1 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13047151 | 0.96 | NPSR1 (0.55) | NPSR1TP53LMNAMEN1ALDH1A1 | |
| SCHEMBL11919951 | 0.89 | TNKS2 (0.66) | NPSR1TP53LMNAMEN1ALDH1A1 | |
| SCHEMBL11919953 | 0.86 | TNKS2 (0.64) | NPSR1TP53LMNAMEN1ALDH1A1 | |
| SCHEMBL11919952 | 0.86 | TNKS2 (0.64) | NPSR1TP53LMNAMEN1ALDH1A1 | |
| SCHEMBL11919938 | 0.84 | TNKS2 (0.48) | NPSR1TP53LMNAMEN1ALDH1A1 | |
| SCHEMBL11919940 | 0.80 | TNKS2 (0.47) | NPSR1TP53LMNAMEN1ALDH1A1 | |
| SCHEMBL11919941 | 0.80 | TNKS2 (0.47) | NPSR1TP53LMNAMEN1ALDH1A1 | |
| SCHEMBL13049102 | 0.80 | NPSR1 (0.59) | NPSR1TP53LMNAMEN1ALDH1A1 | |
| SCHEMBL13049099 | 0.79 | NPSR1 (0.37) | NPSR1TP53LMNAMEN1ALDH1A1 | |
| SCHEMBL11919960 | 0.79 | TNKS2 (0.45) | NPSR1TP53LMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139966-A1 | AZOLE DERIVATIVES AS WTN PATHWAY INHIBITORS | OSLO UNIVERSITY HOSPITAL HF (NO) | 2010-12-09 | — | — | WO | disclosed |