Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 8/20 | 0.67 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 12/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 12/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717834 | 0.91 | PRKDC (0.81) | PRKDCMTORPIK3CDPIK3CBPIK3CA | |
| SCHEMBL13049069 | 0.88 | PRKDC (0.61) | PRKDCMTORPIK3CDPIK3CBPIK3CA | |
| SCHEMBL13049328 | 0.83 | PRKDC (0.57) | PRKDCPIK3CDPIK3CBPIK3CA | |
| SCHEMBL13049915 | 0.82 | PRKDC (0.58) | PRKDCPIK3CDPIK3CBPIK3CA | |
| SCHEMBL13050063 | 0.81 | PRKDC (0.55) | PRKDCMTORPIK3CDPIK3CBPIK3CA | |
| SCHEMBL4109272 | 0.80 | PRKDC (1.00) | PRKDCMTORPIK3CDPIK3CBPIK3CA | |
| SCHEMBL3717836 | 0.80 | PRKDC (0.81) | PRKDCMTORPIK3CDPIK3CBPIK3CA | |
| SCHEMBL13049300 | 0.79 | PRKDC (0.55) | PRKDCMTORPIK3CDPIK3CBPIK3CA | |
| SCHEMBL13049071 | 0.79 | PRKDC (0.53) | PRKDCPIK3CDPIK3CBPIK3CA | |
| SCHEMBL13050051 | 0.79 | PRKDC (0.54) | PRKDCMTORPIK3CDPIK3CBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136778-A1 | DIBENZOTHIOPHENE DERIVATIVES AS DNA- PK INHIBITORS | KUDOS PHARMACEUTICALS LIMITED (GB) | 2010-12-02 | — | — | WO | disclosed |