Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115882 | 0.86 | BTK (0.35) | AAK1HDAC4HDAC1HDAC6CTSL | |
| SCHEMBL13048217 | 0.86 | BTK (0.35) | AAK1HDAC4HDAC1HDAC6CTSL | |
| SCHEMBL2622111 | 0.86 | BTK (0.35) | AAK1HDAC4HDAC1HDAC6CTSL | |
| SCHEMBL2622110 | 0.85 | AAK1 (0.35) | AAK1HDAC4HDAC1HDAC6CTSL | |
| SCHEMBL2113517 | 0.85 | AAK1 (0.35) | AAK1HDAC4HDAC1HDAC6CTSL | |
| SCHEMBL13049352 | 0.84 | HDAC4 (0.33) | AAK1HDAC4HDAC1HDAC6CTSL | |
| SCHEMBL2442182 | 0.78 | AAK1 (0.42) | AAK1HDAC4HDAC1HDAC6CTSL | |
| SCHEMBL12329857 | 0.78 | AAK1 (0.42) | AAK1HDAC4HDAC1HDAC6CTSL | |
| SCHEMBL2117361 | 0.78 | XIAP (0.42) | CTSLGAACTSK | |
| SCHEMBL2622112 | 0.78 | XIAP (0.42) | CTSLGAACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138496-A1 | IAP INHIBITORS | TETRALOGIC PHARMACEUTICALS CORP. (US) | 2010-12-02 | — | — | WO | disclosed |