⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19063003 | 0.75 | — | — | |
| SCHEMBL13662343 | 0.73 | — | — | |
| SCHEMBL19774484 | 0.71 | — | — | |
| SCHEMBL22135658 | 0.69 | — | — | |
| SCHEMBL18414187 | 0.69 | — | — | |
| SCHEMBL19797327 | 0.69 | — | — | |
| SCHEMBL16090746 | 0.69 | — | — | |
| SCHEMBL21746096 | 0.69 | — | — | |
| SCHEMBL15047185 | 0.69 | — | — | |
| SCHEMBL12824460 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287459-A1 | PURINYL-N-HYDROXYL PYRIMIDINE FORMAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | Guizhou Bailing Enterprise Group Pharmaceutical Co., Ltd. (CN) | 2018-02-28 | — | — | EP | disclosed |
| EP-2640722-B1 | PYRAZOLOPYRIDINES AND THEIR USE AS TYK2 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2015-11-04 | — | — | EP | disclosed |
| WO-2010138791-A1 | ANTIVIRAL COMPOUNDS COMPOSED OF THREE LINKED ARYL MOIETIES TO TREAT DISEASES SUCH AS HEPATITIS C | SCHERING CORPORATION (US) | 2010-12-02 | — | — | WO | disclosed |