Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 20/20 | 0.73 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.57 |
| ▸ | CALCA | P06881 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13050743 | 1.00 | CALCRL (0.73) | CALCRLRAMP1CALCA | |
| SCHEMBL13050740 | 1.00 | CALCRL (0.73) | CALCRLRAMP1CALCA | |
| SCHEMBL2766016 | 0.91 | CALCRL (0.74) | CALCRLRAMP1CALCA | |
| SCHEMBL13036893 | 0.85 | CALCRL (0.66) | CALCRLRAMP1CALCA | |
| SCHEMBL13025490 | 0.85 | CALCRL (0.66) | CALCRLRAMP1CALCA | |
| SCHEMBL13345743 | 0.83 | CALCRL (0.61) | CALCRLRAMP1CALCA | |
| SCHEMBL13025489 | 0.83 | CALCRL (0.61) | CALCRLRAMP1CALCA | |
| SCHEMBL13025498 | 0.83 | CALCRL (0.61) | CALCRLRAMP1CALCA | |
| SCHEMBL13025486 | 0.83 | CALCRL (0.61) | CALCRLRAMP1CALCA | |
| SCHEMBL19236114 | 0.81 | CALCRL (0.81) | CALCRLRAMP1CALCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010144293-A1 | SYNTHESIS OF TELCAGEPANT AND INTERMEDIATES THEREOF | MERCK SHARP & DOHME CORP. (US) | 2010-12-16 | — | — | WO | disclosed |