SCHEMBL13054818

SCHEMBL13054818

COCOc1ccc(C(C)(C)c2ccc(OC)c(-c3ccccc3)c2)cc1-c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 4/20 0.45
EGFR P00533 3/20 0.43
CASR P41180 3/20 0.40
ADRB2 P07550 1/20 0.40
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
CTSA P10619 6/20 0.39
SYK P43405 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12325420 0.88 CASR (0.47) PTGDR2CASRMAOAMAOB
SCHEMBL14465958 0.87 EGFR (0.52) PTGDR2EGFRADRB2CTSA
SCHEMBL13054831 0.86 PTGDR2 (0.37) PTGDR2EGFRCASRADRB2CTSA
SCHEMBL12736317 0.81 CASR (0.45) PTGDR2CASRMAOAMAOBCTSA
SCHEMBL15590929 0.81 EGFR (0.46) PTGDR2EGFRCTSA
SCHEMBL2315335 0.80 PTGDR2 (0.52) PTGDR2ADRB2
SCHEMBL12438736 0.77 BACE1 (0.58) PTGDR2MAOAMAOBCTSA
SCHEMBL20524224 0.76 EGFR (0.40) PTGDR2EGFRADRB2
SCHEMBL31139391 0.76 EGFR (0.40) PTGDR2EGFRADRB2
SCHEMBL13054812 0.76 KDM4E (0.43) EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8808951-B2 Electrophotographic photosensitive body HODOGAYA CHEMICAL CO., LTD. (JP) 2014-08-19 US disclosed
US-20130266343-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY HODOGAYA CHEMICAL CO LTD (JP) 2013-10-10 US disclosed
US-20100291480-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY HODOGAYA CHEMICAL CO., LTD. (JP) 2010-11-18 US disclosed
US-7790342-B2 Electrophotographic photosensitive body HODOGAYA CHEMICAL CO., LTD. (JP) 2010-09-07 US disclosed
US-20090226830-A1 Using in combination a p-terphenyl compound, N-N'-diphenyl-N,N'-di-p- tolyl-4,4''-diamino-p-terphenyl, as charge transport agent and a polycarbonate homo- and copolymer of bisphenol A or analogues as binder; providing an high photosensitive, improved residual potential and high durability HODOGAYA CHEMICAL CO., LTD. (JP) 2009-09-10 US disclosed