SCHEMBL13062140

SCHEMBL13062140

O=C(O)CC[C@H](NC(=O)N[C@@H](CCC(=O)NCCNC(=O)CC[C@@H](NC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)NC(=S)Nc1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)c1)C(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CA9 Q16790 13/20 0.52
▸ CA1 P00915 12/20 0.52
▸ CA2 P00918 12/20 0.52
▸ CA12 O43570 6/20 0.52
▸ CA14 Q9ULX7 2/20 0.52
▸ CA7 P43166 2/20 0.52
▸ FOLH1 Q04609 2/20 0.51
▸ ALB P02768 2/20 0.51
▸ ELF3 P78545 2/20 0.48
▸ MED23 Q9ULK4 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14306442 0.98 CA9 (0.53) CA9CA1CA2CA12CA14
SCHEMBL23118947 0.97 CA9 (0.49) CA9CA1CA2CA12CA14
SCHEMBL19354955 0.96 CA9 (0.52) CA9CA1CA2CA12CA14
SCHEMBL13062142 0.95 CA9 (0.49) CA9CA1CA2CA12CA14
SCHEMBL21335460 0.95 CA9 (0.49) CA9CA1CA2CA12CA14
SCHEMBL23716495 0.95 CA9 (0.49) CA9CA1CA2CA12CA14
SCHEMBL21892235 0.94 CA9 (0.48) CA9CA1CA2CA12CA14
SCHEMBL13062332 0.93 CA9 (0.57) CA9CA1CA2CA12CA14
SCHEMBL14306441 0.93 CA9 (0.50) CA9CA1CA2CA12CA14
SCHEMBL22639566 0.93 CA9 (0.49) CA9CA1CA2CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230346752-A1 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING PURDUE RESEARCH FOUNDATION 2023-11-02 — — US disclosed
US-20230346752-A1 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING PURDUE RESEARCH FOUNDATION 2023-11-02 — — US disclosed
US-11369590-B2 PSMA binding ligand-linker conjugates and methods for using PURDUE RESEARCH FOUNDATION (US) 2022-06-28 — — US disclosed
EP-3656403-B1 PREPARATION PROCESS OF PSMA BINDING LIGAND-LINKER CONJUGATES PURDUE RESEARCH FOUNDATION (US) 2022-05-11 — — EP disclosed
US-11318121-B2 PSMA binding ligand-linker conjugates and methods for using PURDUE RESEARCH FOUNDATION (US) 2022-05-03 — — US disclosed
US-20210338641-A1 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING PURDUE RESEARCH FOUNDATION 2021-11-04 — — US disclosed
US-20210322388-A1 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING PURDUE RESEARCH FOUNDATION 2021-10-21 — — US disclosed
US-11083710-B2 PSMA binding ligand-linker conjugates and methods for using PURDUE RESEARCH FOUNDATION (US) 2021-08-10 — — US disclosed
EP-3858347-A2 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING Purdue Research Foundation (US) 2021-08-04 — — EP disclosed
US-10828282-B2 PSMA binding ligand-linker conjugates and methods for using PURDUE RESEARCH FOUNDATION (US) 2020-11-10 — — US disclosed
US-20200155696-A1 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING PURDUE RESEARCH FOUNDATION 2020-05-21 — — US disclosed
US-10646581-B2 PSMA binding ligand-linker conjugates and methods for using PURDUE RESEARCH FOUNDATION (US) 2020-05-12 — — US disclosed
US-10624969-B2 PSMA binding ligand-linker conjugates and methods for using PURDUE RESEARCH FOUNDATION (US) 2020-04-21 — — US disclosed
US-10624971-B2 PSMA binding ligand-linker conjugates and methods for using PURDUE RESEARCH FOUNDATION (US) 2020-04-21 — — US disclosed
US-10517956-B2 PSMA binding ligand-linker conjugates and methods for using PURDUE RESEARCH FOUNDATION (US) 2019-12-31 — — US disclosed
US-10406240-B2 PSMA binding ligand-linker conjugates and methods for using PURDUE RESEARCH FOUNDATION (US) 2019-09-10 — — US disclosed
US-20160067341-A1 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING PURDUE RESEARCH FOUNDATION 2016-03-10 — — US disclosed
US-9193763-B2 PSMA binding ligand-linker conjugates and methods for using PURDUE RESEARCH FOUNDATION (US) 2015-11-24 — — US disclosed
US-20100324008-A1 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING PURDUE RESEARCH FOUNDATION (US) 2010-12-23 — — US disclosed
WO-2009026177-A1 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING PURDUE RESEARCH FOUNDATION (US) 2009-02-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10406240-B2 PSMA binding ligand-linker conjugates and methods for using FOLH1, KLK3, PSMA1 CA9 121/4885CA1 431/4885CA2 1961/4885
US-11083710-B2 PSMA binding ligand-linker conjugates and methods for using FOLH1, KLK3, PSMA1 CA9 121/4885CA1 431/4885CA2 1961/4885
US-10828282-B2 PSMA binding ligand-linker conjugates and methods for using FOLH1, KLK3, PSMA1 CA9 121/4885CA1 431/4885CA2 1961/4885
US-20210322388-A1 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING FOLH1, KLK3, PSMA1 CA9 121/4885CA1 431/4885CA2 1961/4885
US-11369590-B2 PSMA binding ligand-linker conjugates and methods for using FOLH1, KLK3, PSMA1 CA9 121/4885CA1 431/4885CA2 1961/4885
US-11318121-B2 PSMA binding ligand-linker conjugates and methods for using FOLH1, KLK3, PSMA1 CA9 121/4885CA1 431/4885CA2 1961/4885
US-10624971-B2 PSMA binding ligand-linker conjugates and methods for using FOLH1, KLK3, PSMA1 CA9 121/4885CA1 431/4885CA2 1961/4885
US-10624969-B2 PSMA binding ligand-linker conjugates and methods for using FOLH1, KLK3, PSMA1 CA9 121/4885CA1 431/4885CA2 1961/4885
US-20210338641-A1 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING FOLH1, KLK3, PSMA1 CA9 121/4885CA1 431/4885CA2 1961/4885
US-10517956-B2 PSMA binding ligand-linker conjugates and methods for using FOLH1, KLK3, PSMA1 CA9 121/4885CA1 431/4885CA2 1961/4885
US-20100324008-A1 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING FOLH1, KLK3, PSMA1 CA9 121/4885CA1 431/4885CA2 1961/4885
US-10646581-B2 PSMA binding ligand-linker conjugates and methods for using FOLH1, KLK3, PSMA1 CA9 121/4885CA1 431/4885CA2 1961/4885
US-20160067341-A1 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING FOLH1, KLK3, PSMA1 CA9 121/4885CA1 431/4885CA2 1961/4885
US-20200155696-A1 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING FOLH1, KLK3, PSMA1 CA9 121/4885CA1 431/4885CA2 1961/4885
US-20230346752-A1 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING FOLH1, KLK3, PSMA1 CA9 121/4885CA1 431/4885CA2 1961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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