Phenothrin

Phenothrin

SCHEMBL13062899

CC(C)=C[C@H]1C(C(=O)OCc2cccc(Oc3ccccc3)c2)C1(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 1.00
LMNA P02545 2/20 0.84
ADRA2A P08913 1/20 0.84
CNR1 P21554 1/20 0.84
ATM Q13315 1/20 0.84
L3MBTL1 Q9Y468 1/20 0.84
ALDH1A1 P00352 1/20 0.48
CYP1A2 P05177 2/20 0.47
CYP2C19 P33261 2/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
FKBP1A P62942 3/20 0.45
MMP1 P03956 2/20 0.45
TSHR P16473 1/20 0.45
MMP2 P08253 1/20 0.44
MMP9 P14780 1/20 0.44
MMP12 P39900 1/20 0.44
CETP P11597 1/20 0.42
FFAR1 O14842 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenothrin SCHEMBL29455099 1.00 TDP1 (1.00) TDP1LMNAADRA2ACNR1ATM
Phenothrin SCHEMBL29511514 1.00 TDP1 (1.00) TDP1LMNAADRA2ACNR1ATM
Phenothrin SCHEMBL31558671 1.00 TDP1 (1.00) TDP1LMNAADRA2ACNR1ATM
Phenothrin SCHEMBL13062903 1.00 TDP1 (1.00) TDP1LMNAADRA2ACNR1ATM
Phenothrin SCHEMBL74649 1.00 TDP1 (1.00) TDP1LMNAADRA2ACNR1ATM
Phenothrin SCHEMBL28676442 1.00 TDP1 (1.00) TDP1LMNAADRA2ACNR1ATM
Phenothrin SCHEMBL24119149 1.00 TDP1 (1.00) TDP1LMNAADRA2ACNR1ATM
Phenothrin SCHEMBL2963269 1.00 TDP1 (1.00) TDP1LMNAADRA2ACNR1ATM
Phenothrin SCHEMBL8649333 1.00 TDP1 (1.00) TDP1LMNAADRA2ACNR1ATM
Phenothrin SCHEMBL8852430 1.00 TDP1 (1.00) TDP1LMNAADRA2ACNR1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7858334-B2 Degradation of hydrophobic ester pesticides and toxins COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2010-12-28 US disclosed