Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.56 |
| ▸ | PIK3CB | P42338 | 20/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 20/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 17/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13063148 | 1.00 | PIK3CD (0.56) | PIK3CDPIK3CBPIK3CGPIK3CACYP3A4 | |
| SCHEMBL3772557 | 0.86 | PIK3CD (0.70) | PIK3CDPIK3CBPIK3CGPIK3CACYP3A4 | |
| SCHEMBL3781552 | 0.86 | PIK3CD (0.70) | PIK3CDPIK3CBPIK3CGPIK3CACYP3A4 | |
| SCHEMBL2717116 | 0.86 | PIK3CD (0.70) | PIK3CDPIK3CBPIK3CGPIK3CACYP3A4 | |
| SCHEMBL2718319 | 0.82 | PIK3CD (0.48) | PIK3CDPIK3CBPIK3CGPIK3CACYP3A4 | |
| SCHEMBL2718285 | 0.82 | PIK3CD (0.48) | PIK3CDPIK3CBPIK3CGPIK3CACYP3A4 | |
| SCHEMBL4100943 | 0.82 | PIK3CD (0.48) | PIK3CDPIK3CBPIK3CGPIK3CACYP3A4 | |
| SCHEMBL13063175 | 0.81 | PIK3CD (0.85) | PIK3CDPIK3CBPIK3CGPIK3CACYP3A4 | |
| SCHEMBL2014889 | 0.77 | PIK3CD (0.49) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL12632060 | 0.77 | PIK3CD (0.47) | PIK3CDPIK3CBPIK3CGPIK3CACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331306-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | AMGEN INC. (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331306-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | MCL1, BCL9, MALT1 | PIK3CD 15/4885PIK3CB 35/4885PIK3CG 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.