Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | CHKA | P35790 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14765573 | 0.84 | KDM4E (0.64) | KDM4ERAB9ANPC1MITFALDH1A1 | |
| SCHEMBL10168651 | 0.83 | KDM4E (0.44) | KDM4ERAB9ANPC1MITFALDH1A1 | |
| SCHEMBL10136969 | 0.80 | KDM4E (0.41) | KDM4ERAB9ANPC1MITFALDH1A1 | |
| SCHEMBL10136985 | 0.75 | KDM4E (0.46) | KDM4ERAB9ANPC1MITFALDH1A1 | |
| SCHEMBL10136900 | 0.68 | KDM4E (0.80) | KDM4ERAB9ANPC1MITFALDH1A1 | |
| SCHEMBL10168658 | 0.67 | KDM4E (0.51) | KDM4ERAB9ANPC1MITFALDH1A1 | |
| SCHEMBL217044 | 0.63 | MAPT (1.00) | KDM4ERAB9ANPC1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL28420480 | 0.61 | MAPT (0.94) | KDM4ERAB9ANPC1ALDH1A1HTT | |
| SCHEMBL25342075 | 0.61 | BCHE (0.42) | KDM4ERAB9ANPC1MITFALDH1A1 | |
| SCHEMBL2926836 | 0.60 | MAPT (0.89) | KDM4ERAB9ANPC1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2259061-A2 | Boronic acid derivatives | The Regents of The University of California (US) | 2010-12-08 | — | — | EP | disclosed |