Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12832801 | 0.95 | HDAC1 (0.50) | TDP1HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL13933074 | 0.81 | HDAC1 (0.50) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL831000 | 0.81 | HDAC1 (0.50) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL17262864 | 0.81 | HDAC1 (0.50) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL8117338 | 0.80 | TDP1 (0.50) | TDP1TSHRPRMT1F2ST14 | |
| SCHEMBL4026012 | 0.78 | TDP1 (0.59) | TDP1TSHRPRMT1F2ST14 | |
| SCHEMBL4026782 | 0.78 | TDP1 (0.59) | TDP1TSHRPRMT1F2ST14 | |
| SCHEMBL8207344 | 0.78 | TDP1 (0.59) | TDP1TSHRPRMT1F2ST14 | |
| SCHEMBL10562442 | 0.78 | TDP1 (0.59) | TDP1TSHRPRMT1F2ST14 | |
| SCHEMBL4021022 | 0.78 | TDP1 (0.59) | TDP1TSHRPRMT1F2ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937182-B1 | BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES | BEZWADA BIOMEDICAL LLC (US) | 2010-12-15 | — | — | EP | disclosed |