Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 9/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18056712 | 0.92 | MAPT (0.43) | ELANEESR1MAPTTDP1L3MBTL1 | |
| SCHEMBL12021518 | 0.87 | ELANE (0.51) | ELANEMEN1KMT2AALDH1A1 | |
| SCHEMBL13191439 | 0.86 | ELANE (0.47) | ELANEESR1ESR2MAPTTDP1 | |
| SCHEMBL807094 | 0.86 | ELANE (0.46) | ELANETDP1BCHEKDM4EPOLB | |
| SCHEMBL18056745 | 0.86 | ELANE (0.37) | ELANEESR1MAPTTDP1L3MBTL1 | |
| SCHEMBL14679479 | 0.85 | ELANE (0.47) | ELANEESR1ESR2MAPTTDP1 | |
| SCHEMBL12907932 | 0.85 | ELANE (0.44) | ELANEMAPTTDP1L3MBTL1BCHE | |
| SCHEMBL13661694 | 0.84 | MAPT (0.61) | ELANEMAPTTDP1L3MBTL1KDM4E | |
| SCHEMBL25468062 | 0.83 | ELANE (0.46) | ELANEMAPTTDP1L3MBTL1BCHE | |
| SCHEMBL21030113 | 0.83 | ELANE (0.54) | ELANEKDM4EPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9753385-B2 | Electrophotographic photosensitive member, method for manufacturing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2017-09-05 | — | — | US | disclosed |
| US-20100329748-A1 | DEVELOPING DEVICE AND IMAGE FORMING APPARATUS USING THE DEVELOPING DEVICE | RICOH COMPANY, LTD. (JP) | 2010-12-30 | — | — | US | disclosed |