SCHEMBL13064115

CC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H]1CC(=O)NCCCCC(C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O

nearest known ligand 0.59

Predicted protein targets (top 19)

	gene	UniProt	supporting neighbours	confidence
▸	MC4R	P32245	18/20	0.59

▸	MC1R	Q01726	6/20	0.59

▸	MC5R	P33032	5/20	0.59

▸	MC3R	P41968	6/20	0.59

▸	TUBB4A	P04350	2/20	0.58

▸	TUBB	P07437	2/20	0.58

▸	TUBA3C	P0DPH7	2/20	0.58

▸	TUBA1B	P68363	2/20	0.58

▸	TUBA4A	P68366	2/20	0.58

▸	TUBB4B	P68371	2/20	0.58

▸	TUBB3	Q13509	2/20	0.58

▸	TUBB2A	Q13885	2/20	0.58

▸	TUBB8	Q3ZCM7	2/20	0.58

▸	TUBA3E	Q6PEY2	2/20	0.58

▸	TUBA1A	Q71U36	2/20	0.58

▸	TUBA1C	Q9BQE3	2/20	0.58

▸	TUBB6	Q9BUF5	2/20	0.58

▸	TUBB2B	Q9BVA1	2/20	0.58

▸	TUBB1	Q9H4B7	2/20	0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10307942	1.00	MC4R (0.59)	MC4RMC1RMC5RMC3RTUBB4A
SCHEMBL10307923	0.96	MC4R (0.64)	MC4RMC1RMC5RMC3RTUBB4A
SCHEMBL10307956	0.96	MC4R (0.64)	MC4RMC1RMC5RMC3RTUBB4A
SCHEMBL13063966	0.96	MC4R (0.64)	MC4RMC1RMC5RMC3RTUBB4A
SCHEMBL10308034	0.96	MC4R (0.61)	MC4RMC1RMC5RMC3RTUBB4A
SCHEMBL19473806	0.96	MC4R (0.64)	MC4RMC1RMC5RMC3RTUBB4A
SCHEMBL10307921	0.96	MC4R (0.64)	MC4RMC1RMC5RMC3RTUBB4A
SCHEMBL19473970	0.96	MC4R (0.61)	MC4RMC1RMC5RMC3RTUBB4A
SCHEMBL13063933	0.96	MC4R (0.64)	MC4RMC1RMC5RMC3RTUBB4A
SCHEMBL19473971	0.95	FCGRT (0.60)	MC4RMC1RMC5RMC3RTUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2010144344-A2	MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES	PALATIN TECHNOLOGIES, INC. (US)	2010-12-16	—	—	WO	disclosed