SCHEMBL13064117

SCHEMBL13064117

CC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H]1CC(=O)NCCCC[C@@H](C(=O)O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O

nearest known ligand 0.66

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 18/20 0.66
▸ MC3R P41968 6/20 0.66
▸ MC1R Q01726 5/20 0.66
▸ MC5R P33032 5/20 0.66
▸ TUBB4A P04350 2/20 0.57
▸ TUBB P07437 2/20 0.57
▸ TUBA3C P0DPH7 2/20 0.57
▸ TUBA1B P68363 2/20 0.57
▸ TUBA4A P68366 2/20 0.57
▸ TUBB4B P68371 2/20 0.57
▸ TUBB3 Q13509 2/20 0.57
▸ TUBB2A Q13885 2/20 0.57
▸ TUBB8 Q3ZCM7 2/20 0.57
▸ TUBA3E Q6PEY2 2/20 0.57
▸ TUBA1A Q71U36 2/20 0.57
▸ TUBA1C Q9BQE3 2/20 0.57
▸ TUBB6 Q9BUF5 2/20 0.57
▸ TUBB2B Q9BVA1 2/20 0.57
▸ TUBB1 Q9H4B7 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13064154 0.98 MC4R (0.67) MC4RMC3RMC1RMC5RTUBB4A
SCHEMBL10307919 0.97 MC4R (0.63) MC4RMC3RMC1RMC5RTUBB4A
Bremelanotide SCHEMBL20356841 0.96 MC4R (0.71) MC4RMC3RMC1RMC5R
Bremelanotide SCHEMBL13574795 0.96 MC4R (0.71) MC4RMC3RMC1RMC5R
Bremelanotide SCHEMBL29405727 0.96 MC4R (0.71) MC4RMC3RMC1RMC5R
Bremelanotide SCHEMBL14498253 0.96 MC4R (0.71) MC4RMC3RMC1RMC5R
Bremelanotide SCHEMBL20356840 0.96 MC4R (0.71) MC4RMC3RMC1RMC5R
Bremelanotide SCHEMBL29575881 0.96 MC4R (0.70) MC4RMC3RMC1RMC5R
SCHEMBL19473806 0.96 MC4R (0.64) MC4RMC3RMC1RMC5RTUBB4A
SCHEMBL10307921 0.96 MC4R (0.64) MC4RMC3RMC1RMC5RTUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10632171-B2 Melanocortin receptor-specific peptides PALATIN TECHNOLOGIES, INC. (US) 2020-04-28 — — US disclosed
US-20190216887-A1 Melanocortin Receptor-Specific Peptides PALATIN TECHNOLOGIES INC (US) 2019-07-18 — — US disclosed
US-10179804-B2 Melanocortin receptor-specific peptides PALATIN TECHNOLOGIES, INC. (US) 2019-01-15 — — US disclosed
EP-2440227-B1 MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES PALATIN TECHNOLOGIES INC (US) 2017-10-18 — — EP disclosed
US-20160318977-A1 Melanocortin Receptor-Specific Peptides PALATIN TECHNOLOGIES INC (US) 2016-11-03 — — US disclosed
US-9458201-B2 Melanocortin receptor-specific heptapeptides PALATIN TECHNOLOGIES, INC. (US) 2016-10-04 — — US disclosed
US-20140357575-A1 Melanocortin Receptor-Specific Heptapeptides PALATIN TECHNOLOGIES INC (US) 2014-12-04 — — US disclosed
WO-2010144344-A2 MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES PALATIN TECHNOLOGIES, INC. (US) 2010-12-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10179804-B2 Melanocortin receptor-specific peptides MC1R, MC3R, MC5R MC4R 4/4885MC3R 2/4885MC1R 1/4885
US-20140357575-A1 Melanocortin Receptor-Specific Heptapeptides MC5R, MC1R, MC3R MC4R 5/4885MC3R 3/4885MC1R 2/4885
US-20190216887-A1 Melanocortin Receptor-Specific Peptides MC1R, MC3R, MC4R MC4R 3/4885MC3R 2/4885MC1R 1/4885
US-20160318977-A1 Melanocortin Receptor-Specific Peptides MC1R, MC3R, MC5R MC4R 4/4885MC3R 2/4885MC1R 1/4885
US-10632171-B2 Melanocortin receptor-specific peptides MC1R, MC3R, MC4R MC4R 3/4885MC3R 2/4885MC1R 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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