Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | OGG1 | O15527 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306561 | 1.00 | CNR2 (0.47) | CNR2HPGDKDM4EALDH1A1CNR1 | |
| SCHEMBL1308527 | 0.92 | HPGD (0.49) | CNR2HPGDKDM4EALDH1A1TDP1 | |
| SCHEMBL1308523 | 0.92 | HPGD (0.49) | CNR2HPGDKDM4EALDH1A1TDP1 | |
| SCHEMBL1305811 | 0.91 | HPGD (0.45) | HPGDKDM4EALDH1A1TDP1OGG1 | |
| SCHEMBL29488485 | 0.91 | HPGD (0.45) | HPGDKDM4EALDH1A1TDP1OGG1 | |
| SCHEMBL1305817 | 0.91 | HPGD (0.45) | HPGDKDM4EALDH1A1TDP1OGG1 | |
| SCHEMBL22403025 | 0.88 | HTR1B (0.45) | CNR2HPGDKDM4EALDH1A1CNR1 | |
| SCHEMBL12115952 | 0.87 | CNR2 (0.48) | CNR2HPGDKDM4EALDH1A1CNR1 | |
| SCHEMBL1306595 | 0.86 | CNR2 (0.41) | CNR2HPGDKDM4EALDH1A1CNR1 | |
| SCHEMBL1308955 | 0.86 | CNR2 (0.41) | CNR2HPGDKDM4EALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053435-B2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-11-08 | — | — | US | disclosed |