Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845091 | 0.91 | KMT2A (0.49) | KMT2ATSHRHPGDMEN1MAPT | |
| SCHEMBL21338153 | 0.78 | HPGD (0.71) | KMT2ATSHRHPGDMEN1HTT | |
| SCHEMBL13066752 | 0.77 | KMT2A (0.49) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8735682 | 0.74 | KMT2A (0.70) | KMT2ATSHRHPGDMEN1MAPT | |
| SCHEMBL30162631 | 0.72 | KMT2A (1.00) | KMT2AHPGDMEN1MAPTKDM4E | |
| SCHEMBL377259 | 0.72 | KMT2A (1.00) | KMT2AHPGDMEN1MAPTKDM4E | |
| SCHEMBL5309782 | 0.72 | HPGD (0.67) | KMT2ATSHRHPGDMEN1HTT | |
| SCHEMBL13067261 | 0.71 | KMT2A (0.70) | KMT2AHPGDMEN1MAPTKDM4E | |
| SCHEMBL681071 | 0.71 | KMT2A (0.70) | KMT2AHPGDMEN1MAPTKDM4E | |
| SCHEMBL120913 | 0.71 | KMT2A (0.70) | KMT2AHPGDMEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432776-B1 | METHYL SULFANYL PYRIMIDINES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS | UNIV LAVAL (CA) | 2019-09-11 | — | — | EP | disclosed |
| WO-2010132999-A1 | METHYL SULFANYL PYRMIDMES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS | CHLORION PHARMA, INC. (CA) | 2010-11-25 | — | — | WO | disclosed |