Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | ACR | P10323 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 2/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13067346 | 0.86 | MAPT (0.41) | MAPTKMT2AMEN1PRSS1ACR | |
| SCHEMBL12822564 | 0.78 | MAPT (0.33) | MAPTKMT2AMEN1APPHIF1A | |
| SCHEMBL12823900 | 0.78 | APP (0.32) | MAPTAPPCYP2C19 | |
| SCHEMBL9906005 | 0.77 | ESR1 (0.40) | MAPTGAAKMT2AMEN1PRSS1 | |
| SCHEMBL12717495 | 0.75 | ALOX5AP (0.33) | MAPT | |
| SCHEMBL13586617 | 0.75 | PTPN7 (0.30) | — | |
| SCHEMBL13066971 | 0.75 | SCN1A (0.33) | MAPTCYP2C19 | |
| SCHEMBL12822944 | 0.75 | ALOX5AP (0.33) | MAPT | |
| SCHEMBL15343568 | 0.74 | FASN (0.35) | — | |
| SCHEMBL13066969 | 0.74 | F2 (0.33) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838087-B2 | Benzene derivative, liquid crystal composition and liquid crystal display device | CHISSO CORPORATION (JP) | 2010-11-23 | — | — | US | disclosed |