Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.45 |
| ▸ | EDNRA | P25101 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10002027 | 0.89 | CYP1A2 (0.64) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| SCHEMBL10036518 | 0.85 | CYP1A2 (0.41) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| SCHEMBL8532341 | 0.82 | CYP1A2 (0.74) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| SCHEMBL30275401 | 0.82 | CYP1A2 (0.74) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| SCHEMBL5508602 | 0.81 | CYP1A2 (0.64) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| SCHEMBL14178927 | 0.81 | CYP1A2 (0.54) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| SCHEMBL19270962 | 0.80 | CYP1A2 (0.71) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| SCHEMBL13713847 | 0.80 | CYP1A2 (0.71) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| SCHEMBL6412206 | 0.80 | CYP1A2 (0.70) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| SCHEMBL19270960 | 0.79 | CYP1A2 (0.78) | CYP1A2CYP2C19HTTHIF1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773762-B1 | METHODS AND COMPOUNDS FOR DETECTION OF MEDICAL DISORDERS | APOSENSE LTD (IL) | 2010-11-10 | — | — | EP | disclosed |