Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 7/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29244494 | 0.94 | HDAC8 (0.59) | HDAC2HDAC8KDM4ENPC1ALDH1A1 | |
| SCHEMBL29244493 | 0.94 | HDAC8 (0.59) | HDAC2HDAC8KDM4ENPC1ALDH1A1 | |
| SCHEMBL23512738 | 0.84 | KDM4E (0.54) | HDAC2KDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL8250585 | 0.84 | HDAC2 (0.70) | HDAC2HDAC8KDM4ENPC1ALDH1A1 | |
| SCHEMBL3292958 | 0.84 | HDAC2 (0.70) | HDAC2HDAC8KDM4ENPC1ALDH1A1 | |
| SCHEMBL451894 | 0.81 | HDAC8 (0.56) | HDAC2HDAC8KDM4ENPC1ALDH1A1 | |
| SCHEMBL3292397 | 0.81 | HDAC2 (1.00) | HDAC2HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL3292393 | 0.81 | HDAC2 (1.00) | HDAC2HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL1450230 | 0.80 | F3 (0.52) | HDAC2HDAC8ALDH1A1HDAC3HDAC4 | |
| SCHEMBL25146618 | 0.80 | NPC1 (0.55) | HDAC2KDM4ENPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896399-B1 | BIPHENYL AND NAPHTHYL-PHENYL HYDROXAMIC ACID DERIVATIVES | SIGMA TAU IND FARMACEUTI (IT) | 2010-11-17 | — | — | EP | disclosed |