Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11198500 | 0.77 | CRBN (0.36) | CRBNSMN1; SMN2 | |
| SCHEMBL1396870 | 0.70 | — | — | |
| SCHEMBL11185616 | 0.70 | CRBN (0.33) | CRBNSMN1; SMN2 | |
| SCHEMBL21101214 | 0.70 | CRBN (0.33) | CRBN | |
| SCHEMBL5492068 | 0.68 | CRBN (0.36) | CRBN | |
| SCHEMBL21101205 | 0.68 | CRBN (0.32) | CRBN | |
| SCHEMBL6318998 | 0.68 | — | — | |
| SCHEMBL14222411 | 0.66 | — | — | |
| SCHEMBL223245 | 0.66 | — | — | |
| SCHEMBL4515477 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863477-B1 | 3,4-SUBSTITUTED PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF HYPERTENSION | NOVARTIS AG (CH) | 2010-11-03 | — | — | EP | disclosed |