Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13069367 | 0.80 | MAOB (0.42) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13069284 | 0.80 | MAOB (0.42) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14520914 | 0.80 | MAOB (0.42) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14520912 | 0.80 | MAOB (0.42) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13224950 | 0.80 | MAOB (0.42) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6003737 | 0.80 | MAOB (0.42) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6003734 | 0.80 | MAOB (0.42) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13069369 | 0.80 | MAOB (0.42) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13224949 | 0.80 | MAOB (0.42) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6002369 | 0.80 | MAOB (0.42) | MAOBMAOASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2016053-B1 | PROCESS FOR THE SYNTHESIS OF (+) AND (-)-1-ARYL-3-AZABICYCLO[3.1.0]HEXANES | MERCK SHARP & DOHME (US) | 2010-11-10 | — | — | EP | disclosed |
| WO-2007127421-A2 | PROCESS FOR THE SYNTHESIS OF (+) AND (-)-1-ARYL-3-AZABICYCLO[3.1.0]HEXANES | MERCK & CO., INC. (US) | 2007-11-08 | — | — | WO | disclosed |