Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 6/20 | 0.63 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.63 |
| ▸ | GRM5 | P41594 | 1/20 | 0.63 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3421512 | 1.00 | GRIN2B (0.63) | GRIN2BGRIN1SIGMAR1GRM5ESR1 | |
| SCHEMBL3396371 | 1.00 | GRIN2B (0.63) | GRIN2BGRIN1SIGMAR1GRM5ESR1 | |
| SCHEMBL3394371 | 1.00 | GRIN2B (0.63) | GRIN2BGRIN1SIGMAR1GRM5ESR1 | |
| SCHEMBL3392584 | 1.00 | GRIN2B (0.63) | GRIN2BGRIN1SIGMAR1GRM5ESR1 | |
| SCHEMBL7891238 | 1.00 | GRIN2B (0.63) | GRIN2BGRIN1SIGMAR1GRM5ESR1 | |
| SCHEMBL3396212 | 1.00 | GRIN2B (0.63) | GRIN2BGRIN1SIGMAR1GRM5ESR1 | |
| SCHEMBL13069912 | 1.00 | GRIN2B (0.63) | GRIN2BGRIN1SIGMAR1GRM5ESR1 | |
| SCHEMBL3397537 | 0.86 | GRIN1 (0.66) | GRIN2BGRIN1SIGMAR1GRM5 | |
| SCHEMBL3393461 | 0.86 | GRIN1 (0.66) | GRIN2BGRIN1SIGMAR1GRM5 | |
| SCHEMBL13069934 | 0.86 | GRIN1 (0.66) | GRIN2BGRIN1SIGMAR1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246331-A1 | NR2B-selective NMDA-receptor antagonists | Westfälische Wilhelms-Universität Münster (DE) | 2010-11-03 | — | — | EP | disclosed |