Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.49 |
| ▸ | F10 | P00742 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3036898 | 0.88 | AR (0.58) | ARF10RAB9ANPC1NFKB1 | |
| SCHEMBL2570856 | 0.88 | AR (0.62) | ARF10RAB9ANPC1NFKB1 | |
| SCHEMBL2572274 | 0.88 | AR (0.60) | ARF10RAB9ANPC1NFKB1 | |
| SCHEMBL3027962 | 0.87 | F10 (0.46) | ARF10RAB9ANPC1NFKB1 | |
| SCHEMBL2566594 | 0.85 | AR (0.46) | ARF10RAB9ANPC1NFKB1 | |
| SCHEMBL3027914 | 0.79 | F10 (0.61) | ARF10RAB9ANPC1NFKB1 | |
| SCHEMBL3032258 | 0.78 | AR (0.58) | ARF10RAB9ANPC1NFKB1 | |
| SCHEMBL2569536 | 0.78 | AR (0.58) | ARF10RAB9ANPC1NFKB1 | |
| SCHEMBL3027612 | 0.77 | F10 (0.61) | ARF10RAB9ANPC1NFKB1 | |
| SCHEMBL3025755 | 0.77 | AR (0.60) | ARF10RAB9ANPC1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899330-B1 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2010-11-24 | — | — | EP | disclosed |