SCHEMBL130735

SCHEMBL130735

[c]1snc2ccccc12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3621961 0.65
Benzo[1,2,5]Thiadiazole SCHEMBL20886 0.60
SCHEMBL1976862 0.60
Benzo[1,2,5]Thiadiazole SCHEMBL15512538 0.60
Benzo[1,2,5]Thiadiazole SCHEMBL21874941 0.60 MAPT (0.50)
SCHEMBL23981 0.60 MAPT (0.56)
SCHEMBL452301 0.59 MAPT (0.33)
Benzo[1,2,5]Thiadiazole SCHEMBL30785348 0.58 MAPT (0.48)
SCHEMBL6700746 0.54 MAPT (0.65)
Phenazine SCHEMBL29356959 0.54 MAPT (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1598 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3445762-B1 SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS BRISTOL MYERS SQUIBB CO (US) 2023-09-13 EP claimed
WO-2023067322-A1 TRICYCLIC GPR65 MODULATORS Pathios Therapeutics Limited (GB) 2023-04-27 WO claimed
EP-3390370-B1 BIS-TRIAZOLE COMPOUNDS WITH ANTI-BIOFILM AND ANTI-CORROSION PROPERTIES UNIV DE TOULON (FR) 2021-02-03 EP claimed
US-10851108-B2 Substituted bicyclic heterocyclic compounds BRISTOL-MYERS SQUIBB COMPANY (US) 2020-12-01 US claimed
US-20190127380-A1 SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS BRISTOL MYERS SQUIBB CO (US) 2019-05-02 US claimed
WO-2017184662-A1 SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2017-10-26 WO claimed
EP-2029543-B1 SUBSTITUTED 3-CYANOPYRIDINES AS PROTEIN KINASE INHIBITORS WYETH LLC (US) 2015-11-18 EP claimed
EP-2828262-A1 IMIDAZOTRIAZINONE COMPOUNDS Forum Pharmaceuticals Inc. (US) 2015-01-28 EP claimed
US-8933074-B2 1,2-disubstituted heterocyclic compounds FORUM PHARMACEUTICALS INC. (US) 2015-01-13 US claimed
US-20150005265-A1 METHODS AND COMPOSITIONS FOR COMBINATION THERAPY USING P13K/MTOR INHIBITORES TOKAI PHARMACEUTICALS, INC. 2015-01-01 US claimed
EP-0391625-A1 Substituted chromans in the treatment of asthma, arthritis and related diseases PFIZER INC. (US) 1990-10-10 EP claimed
US-4908435-A Aromatic disazo compounds having strong infra-red absorption IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-03-13 US claimed
EP-0313295-A2 Substituted tetralins, chromans and related compounds in the treatment of asthma, arthritis and related diseases PFIZER INC. (US) 1989-04-26 EP claimed
EP-0280434-A2 Aromatic disazo compound IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-08-31 EP claimed
US-4754024-A Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups CIBA-GEIGY CORPORATION 1988-06-28 US claimed
EP-0112285-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1987-03-18 EP claimed
EP-0017558-B1 HETEROCYCLIC AZO COMPOUNDS HAVING SULFATE GROUPS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-10-05 EP claimed
US-4255326-A MONOAZO DYES; THIOPHENE DYES; POLYAMIDES, CELLULOSE ACETATE AND WOOL EASTMAN KODAK COMPANY (US) 1981-03-10 US claimed
US-4247458-A COUPLING DIAZONIUM SALT WITH DISPERSE DYE COUPLER WITH DISPLACEABLE GROUP OTHER THAN HYDROGEN EASTMAN KODAK COMPANY (US) 1981-01-27 US claimed
EP-0017558-A1 Heterocyclic azo compounds having sulfate groups EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1980-10-15 EP claimed