Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.43 |
| ▸ | PDE2A | O00408 | 3/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL356013 | 0.85 | PDE10A (0.58) | POLBSMN1; SMN2PDE10APDE2APDE7A | |
| SCHEMBL167106 | 0.84 | PDE10A (0.46) | POLBSMN1; SMN2PDE10APDE2APDE7A | |
| SCHEMBL4401183 | 0.84 | PDE10A (0.46) | POLBSMN1; SMN2PDE10APDE2APDE7A | |
| SCHEMBL4400124 | 0.83 | PDE10A (0.45) | POLBSMN1; SMN2PDE10APDE2APDE7A | |
| SCHEMBL169419 | 0.83 | AGPAT2 (0.48) | POLBSMN1; SMN2PDE10APDE2APDE7A | |
| SCHEMBL169465 | 0.81 | POLB (0.55) | POLBSMN1; SMN2PDE10APDE2APDE7A | |
| SCHEMBL168094 | 0.81 | PDE10A (0.43) | POLBSMN1; SMN2PDE10APDE2APDE7A | |
| SCHEMBL169484 | 0.81 | PDE10A (0.46) | POLBSMN1; SMN2PDE10APDE2APDE7A | |
| SCHEMBL10284936 | 0.81 | PDE10A (0.43) | POLBSMN1; SMN2PDE10APDE2APDE7A | |
| SCHEMBL354647 | 0.80 | POLB (0.45) | POLBSMN1; SMN2PDE10APDE2APDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010125985-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-04 | — | — | WO | disclosed |