Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 18/20 | 0.64 |
| ▸ | CCR7 | P32248 | 2/20 | 0.56 |
| ▸ | CCR6 | P51684 | 2/20 | 0.56 |
| ▸ | CXCR1 | P25024 | 12/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3801807 | 0.86 | CXCR2 (0.48) | CXCR2CCR7CCR6CXCR1 | |
| SCHEMBL3801804 | 0.86 | CXCR2 (0.48) | CXCR2CCR7CCR6CXCR1 | |
| SCHEMBL13075923 | 0.85 | CXCR2 (0.48) | CXCR2CCR7CCR6CXCR1 | |
| SCHEMBL31114730 | 0.83 | CCR6 (0.66) | CXCR2CCR7CCR6CXCR1 | |
| SCHEMBL23621373 | 0.81 | CXCR2 (0.56) | CXCR2CCR7CCR6CXCR1 | |
| SCHEMBL12263207 | 0.81 | CXCR2 (0.44) | CXCR2CCR7CCR6CXCR1 | |
| SCHEMBL13075926 | 0.81 | CXCR2 (0.72) | CXCR2CXCR1 | |
| SCHEMBL30515708 | 0.81 | CXCR2 (0.72) | CXCR2CXCR1 | |
| SCHEMBL20452343 | 0.81 | CXCR2 (0.72) | CXCR2CXCR1 | |
| SCHEMBL12087143 | 0.80 | CXCR2 (0.82) | CXCR2CCR7CCR6CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010131145-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | disclosed |