Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL298221 | 0.71 | PARP1 (0.51) | SRCEGFRALDH1A1SMN1; SMN2PDPK1 | |
| SCHEMBL20967693 | 0.70 | JAK1 (0.54) | — | |
| SCHEMBL17546677 | 0.70 | MAOB (0.50) | KDM4EALDH1A1HPGDMEN1POLB | |
| SCHEMBL8840857 | 0.70 | MAOB (0.50) | KDM4EALDH1A1HPGDMEN1POLB | |
| SCHEMBL27041249 | 0.70 | KDM4E (0.56) | CYP1A1CYP1B1GUSBCYP1A2PDE3B | |
| SCHEMBL17133045 | 0.68 | MAOB (0.52) | KDM4EALDH1A1HPGDMEN1POLB | |
| SCHEMBL8840801 | 0.68 | MAOB (0.52) | KDM4EALDH1A1HPGDMEN1POLB | |
| SCHEMBL641721 | 0.68 | SRC (0.54) | SRCEGFRALDH1A1SMN1; SMN2PDPK1 | |
| SCHEMBL13075718 | 0.67 | TDP1 (0.59) | SRCSMN1; SMN2 | |
| SCHEMBL20327078 | 0.67 | KDM4E (0.56) | CYP1A1CYP1B1GUSBCYP1A2PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127363-A1 | TOPOSIOMERASE INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-11-04 | — | — | WO | disclosed |