Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13076914 | 0.93 | KCNJ1 (0.80) | KCNJ1KCNH2 | |
| SCHEMBL13076002 | 0.91 | KCNJ1 (0.79) | KCNJ1KCNH2 | |
| SCHEMBL2894170 | 0.88 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL300202 | 0.81 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL10233606 | 0.79 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL2897017 | 0.79 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL287296 | 0.78 | KCNJ1 (0.63) | KCNJ1KCNH2 | |
| Hydrochloric Acid SCHEMBL2890994 | 0.77 | KCNJ1 (0.62) | KCNJ1KCNH2 | |
| SCHEMBL286997 | 0.77 | KCNJ1 (0.83) | KCNJ1KCNH2 | |
| SCHEMBL19367913 | 0.76 | KCNJ1 (0.79) | KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010129379-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME CORP. (US) | 2010-11-11 | — | — | WO | disclosed |