Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2895035 | 0.88 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL2898529 | 0.88 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL2899013 | 0.88 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL287029 | 0.88 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL2899007 | 0.88 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL2895030 | 0.88 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL13076779 | 0.87 | KCNJ1 (0.82) | KCNJ1KCNH2 | |
| SCHEMBL19264195 | 0.86 | KCNJ1 (0.78) | KCNJ1KCNH2 | |
| SCHEMBL19881384 | 0.85 | KCNJ1 (0.80) | KCNJ1KCNH2 | |
| SCHEMBL13076743 | 0.85 | KCNJ1 (1.00) | KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010129379-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME CORP. (US) | 2010-11-11 | — | — | WO | disclosed |