Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 17/20 | 0.51 |
| ▸ | KCNQ2 | O43526 | 17/20 | 0.51 |
| ▸ | KCNE1 | P15382 | 12/20 | 0.51 |
| ▸ | KCNQ1 | P51787 | 12/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203109 | 0.82 | KCNQ3 (0.54) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL5629234 | 0.81 | KCNQ3 (0.60) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL21392142 | 0.78 | NPSR1 (0.47) | KCNQ3KCNQ2RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5629229 | 0.77 | KCNQ3 (0.60) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL30568974 | 0.76 | KCNQ3 (0.64) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL6361424 | 0.76 | KCNQ3 (0.64) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL28603489 | 0.74 | KCNQ3 (0.57) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL2436172 | 0.74 | KCNQ3 (0.67) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL7764259 | 0.74 | KCNQ3 (0.49) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL23177712 | 0.74 | KCNQ3 (0.68) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130034-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-11-18 | — | — | WO | disclosed |