Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 6/20 | 0.36 |
| ▸ | CDK11B | P21127 | 2/20 | 0.36 |
| ▸ | CDK7 | P50613 | 2/20 | 0.36 |
| ▸ | CDK13 | Q14004 | 2/20 | 0.36 |
| ▸ | MAP3K19 | Q56UN5 | 2/20 | 0.36 |
| ▸ | MYLK4 | Q86YV6 | 2/20 | 0.36 |
| ▸ | CDK11A | Q9UQ88 | 2/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 4/20 | 0.36 |
| ▸ | CHUK | O15111 | 5/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.34 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120110 | 0.93 | TTK (0.44) | TTKIKBKBCDK11BCDK7CDK13 | |
| SCHEMBL122056 | 0.91 | TTK (0.43) | TTKIKBKBCDK11BCDK7CDK13 | |
| SCHEMBL174878 | 0.91 | TTK (0.46) | TTKIKBKBCDK11BCDK7CDK13 | |
| SCHEMBL123880 | 0.89 | TTK (0.43) | TTKIKBKBCDK11BCDK7CDK13 | |
| SCHEMBL119528 | 0.89 | TTK (0.42) | TTKIKBKBCDK11BCDK7CDK13 | |
| SCHEMBL121481 | 0.89 | IKBKB (0.44) | TTKIKBKBCDK11BCDK7CDK13 | |
| SCHEMBL3720432 | 0.88 | EPHB4 (0.43) | TTK | |
| SCHEMBL3719730 | 0.86 | TTK (0.42) | TTK | |
| SCHEMBL3722608 | 0.86 | TTK (0.42) | TTK | |
| SCHEMBL121067 | 0.84 | TTK (0.42) | TTKBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010124826-A1 | SUBSTITUTED IMIDAZOQUINOXALINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-11-04 | — | — | WO | disclosed |